Massive Bio — AI SEO & LLM Visibility
Project Overview
This project for Massive Bio was initiated to increase organic visibility in target markets, primarily the US and selected European markets, and to gain presence in AI-powered search results.
Clinical trials and cancer-focused health searches are highly competitive and require strong authority. Therefore, the project adopted a comprehensive strategy beyond traditional SEO growth.
- Achieve organic growth at a global scale
- Build topical authority in cancer and clinical trials
- Gain visibility in AI Overview and LLM-based search results
Project Challenge
Clinical trials and oncology are highly competitive SEO categories. Achieving visibility in this space requires more than content creation; it demands strong authority signals and proper content architecture.
Additionally, a significant portion of health searches are informational in nature and increasingly interpreted by AI Overview and AI-powered answer systems. Therefore, content was structured not only for classic search results but also as reliable references for AI systems.
Implemented Strategy
Preparation & Information Architecture
A site architecture and content categorization system was built to support large-scale content production.
- Planning new category structures
- Defining content categorization rules
- Creating templates for different page types
- Planning page designs and content structures
Technical SEO Infrastructure
The site's technical infrastructure was optimized to support content growth.
- Restructuring site architecture
- Fixing technical SEO issues
- Improving crawl efficiency
- Establishing indexable page structures for new content
Topical Authority & Content Expansion
A broad information ecosystem was built in cancer and health.
- Informative content about cancer types
- Pages covering cancer treatment processes
- Content on cancer treatment side effects
- Lifestyle and exercise recommendations
- Medical information and glossary pages
Authority & AI Visibility
Off-page efforts were implemented to support site authority and accelerate visibility.
- Supporting key pages with backlinks
- Building a strong internal linking structure
- Enhancing contextual strength of content
Results
Authority & Backlink Profile
Increasing DR in a site that already had high authority is challenging, yet efforts achieved a steady increase.
Organic Performance
The broad content coverage helped the site gain visibility for numerous queries in cancer and health.
Content Coverage
The implementation of new content structures significantly increased indexed pages, establishing broad topical coverage.
AI Overview Visibility
Visibility increased particularly for:
- Medical terms and glossary searches
- Cancer types and stages
- Treatment processes
- Symptoms and patient guides
LLM Visibility
Microsoft Copilot & Partner Networks
These increases indicate that the site is becoming a referenced source for AI-powered answer engines.
Conclusion
- Establishment of a broad cancer and health information ecosystem
- Significant growth in organic page count
- Increased visibility for highly competitive health queries
- Strong presence in AI Overview and LLM-based results
The project demonstrates that in high-authority fields like health, combining proper content architecture, broad content coverage, and authority signals can deliver strong visibility in both traditional search and AI-powered systems.
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